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For many researchers, that points directly toward a systemic subcutaneous protocol

[Epub ahead of print] The Safety and Efficacy of LowDose Naltrexone in the Management of Chronic Pain and Inflammation in Multiple Sclerosis, Fibromyalgia, Crohns Disease, and Other Chronic Pain Disorders

Recommended Dosing Protocols Common bodybuilding and recovery-focused protocols include: Subcutaneous: 200500 mcg once or twice daily, near the injury site or in abdominal fat Intramuscular: 200300 mcg directly into the affected muscle, rotating sites Oral: 250500 mcg dissolved in water once daily, though bioavailability may vary Many protocols begin at the lower end, around 200 mcg, during the first week to assess tolerance

I felt very good these two weeks and ramped up the volume and intensity of my training with less than expected fatigue and soreness